Aripiprazole and Sexual Dysfunction: What to Expect

Introduction to Aripiprazole and Sexual Dysfunction

Aripiprazole, commonly known as Abilify, is an atypical antipsychotic medication often prescribed to treat mental health disorders such as schizophrenia, bipolar disorder, and major depressive disorder. While this medication can provide relief for many individuals, it can also cause some unwanted side effects. One of the most common concerns among patients is the potential for sexual dysfunction. In this article, we will discuss the various aspects of Aripiprazole and sexual dysfunction, including what to expect, how to manage it, and when to seek professional help.

Understanding the Link between Aripiprazole and Sexual Dysfunction

The connection between Aripiprazole and sexual dysfunction can be attributed to the medication's effect on dopamine, a neurotransmitter responsible for pleasure, reward, and motivation. Aripiprazole works by partially blocking dopamine receptors in the brain, which can lead to a decrease in sexual desire and arousal. Additionally, this medication can also cause an increase in prolactin levels, a hormone that can contribute to sexual dysfunction.


It is important to note that not everyone taking Aripiprazole will experience sexual dysfunction. The prevalence of this side effect varies depending on factors such as the individual's age, gender, and overall health. Some studies suggest that sexual dysfunction affects approximately 25-50% of individuals taking antipsychotic medications, including Aripiprazole.

Types of Sexual Dysfunction Associated with Aripiprazole

There are several types of sexual dysfunction that can occur as a result of taking Aripiprazole, which may impact both men and women. Some of the most common issues include:

Decreased Libido

One of the most frequently reported side effects is a reduced interest in sexual activity. This can be particularly challenging for individuals who previously enjoyed a healthy sex life, as it may cause strain on relationships and affect overall quality of life.

Erectile Dysfunction

Men taking Aripiprazole may experience difficulty achieving or maintaining an erection. This can be a frustrating and embarrassing issue, often leading to anxiety and stress, which can further exacerbate the problem.

Delayed Ejaculation and Anorgasmia

Some individuals may find it difficult to reach orgasm or may experience a significant delay in ejaculation. This can be frustrating for both partners and may lead to feelings of inadequacy or dissatisfaction with one's sexual performance.

Managing Sexual Dysfunction while Taking Aripiprazole

Fortunately, there are several strategies that can help mitigate the impact of sexual dysfunction caused by Aripiprazole. Some of these include:

Open Communication with Your Partner

Discussing your concerns and experiences with your partner can help to alleviate feelings of embarrassment and stress. This open dialogue can foster a supportive environment, making it easier to navigate the challenges associated with sexual dysfunction.

Consulting Your Healthcare Provider

It is essential to speak with your healthcare provider about any side effects you are experiencing. They can provide guidance on potential treatments or adjustments to your medication regimen that may improve your symptoms.

Considering Alternative Medications

In some cases, your healthcare provider may recommend trying a different antipsychotic medication that has a lower risk of causing sexual dysfunction. However, it is important to weigh the potential benefits and drawbacks of switching medications, as each individual's response to a particular medication can vary.

When to Seek Professional Help for Sexual Dysfunction

If you have tried the above strategies and continue to experience significant sexual dysfunction that is negatively impacting your quality of life, it may be time to seek professional help. A qualified therapist or sexologist can provide guidance and support tailored to your specific needs, helping you to address both the physical and emotional aspects of sexual dysfunction.

Conclusion: Balancing Mental Health and Sexual Well-being

While the potential for sexual dysfunction is an important consideration when taking Aripiprazole, it is essential to remember that the primary goal of this medication is to treat and manage your mental health condition. In many cases, the benefits of Aripiprazole in terms of improved mental well-being can outweigh the potential drawbacks of sexual dysfunction. By openly discussing your concerns with your healthcare provider and partner, and exploring various strategies to manage sexual dysfunction, you can work towards finding a balance between your mental health and sexual well-being.

John Alsop

John Alsop

I'm John Alsop and I'm passionate about pharmaceuticals. I'm currently working in a lab in Sydney, researching new ways to improve the effectiveness of drugs. I'm also involved in a number of clinical trials, helping to develop treatments that can benefit people with different conditions. My writing hobby allows me to share my knowledge about medication, diseases, and supplements with a wider audience.